Lysine and the Na+/K+ Selectivity in Mammalian Voltage-Gated Sodium Channels.

Voltage-gated sodium (Nav) channels are critical in the generation and transmission of neuronal signals in mammals. The crystal structures of several prokaryotic Nav channels determined in recent years inspire the mechanistic studies on their selection upon the permeable cations (especially between...

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Bibliographic Details
Main Authors: Yang Li, Huihui Liu, Mengdie Xia, Haipeng Gong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5008630?pdf=render