Presence of autoantibodies in “seronegative” rheumatoid arthritis associates with classical risk factors and high disease activity

Presence of autoantibodies in “seronegative” rheumatoid arthritis associates with classical risk factors and high disease activity

Abstract Background Rheumatoid arthritis (RA) is classified as seropositive or seronegative, depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti-citrullinated protein antibodies (ACPA), commonly detected using anti-cyclic citrullinated peptide (CCP) assays. Kno...

Full description

Bibliographic Details
Main Authors: Evan Reed, Anna Karin Hedström, Monika Hansson, Linda Mathsson-Alm, Boel Brynedal, Saedis Saevarsdottir, Martin Cornillet, Per-Johan Jakobsson, Rikard Holmdahl, Karl Skriner, Guy Serre, Lars Alfredsson, Johan Rönnelid, Karin Lundberg
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis (RA)
Autoantibodies
Anti-citrullinated protein antibodies (ACPA)
Cyclic citrullinated peptide (CCP)
Rheumatoid factor (RF)
Anti-carbamylated protein antibodies (anti-CarP)
Online Access:http://link.springer.com/article/10.1186/s13075-020-02191-2

Internet

http://link.springer.com/article/10.1186/s13075-020-02191-2

Similar Items