A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation.

Imprinted genes undergo epigenetic modifications during gametogenesis, which lead to transcriptional silencing of either the maternally or the paternally derived allele in the subsequent generation. Previous work has suggested an association between imprinting and the products of retrotransposition,...

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Bibliographic Details
Main Authors: Andrew J Wood, Roland G Roberts, David Monk, Gudrun E Moore, Reiner Schulz, Rebecca J Oakey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1796624?pdf=render