A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation.
Imprinted genes undergo epigenetic modifications during gametogenesis, which lead to transcriptional silencing of either the maternally or the paternally derived allele in the subsequent generation. Previous work has suggested an association between imprinting and the products of retrotransposition,...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1796624?pdf=render |