Oncolytic Viruses: The Power of Directed Evolution

Attempts at developing oncolytic viruses have been primarily based on rational design. However, this approach has been met with limited success. An alternative approach employs directed evolution as a means of producing highly selective and potent anticancer viruses. In this method, diverse viruses...

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Bibliographic Details
Main Authors: Maxine Bauzon, Terry W. Hermiston
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2012/586389