Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line

<p>Abstract</p> <p>Background</p> <p>Management of peritoneal dissemination is the most critical problem in gastric cancer. This study was performed to investigate the inhibitory effects of valproic acid (VPA) on a highly peritoneal-seeding cell line of human scirrhous...

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Main Authors: Yagi Yasumichi, Fushida Sachio, Harada Shinichi, Kinoshita Jun, Makino Isamu, Oyama Katsunobu, Tajima Hidehiro, Fujita Hideto, Takamura Hiroyuki, Ninomiya Itasu, Fujimura Takashi, Ohta Tetsuo, Yashiro Masakazu, Hirakawa Kosei
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/29/1/149