Transcriptome Profiling Reveals Indoxyl Sulfate Should Be Culpable of Impaired T Cell Function in Chronic Kidney Disease

Transcriptome Profiling Reveals Indoxyl Sulfate Should Be Culpable of Impaired T Cell Function in Chronic Kidney Disease

Introduction: Chronic inflammation and immune system dysfunction have been evaluated as major factors in the pathogenesis of chronic kidney disease (CKD), contributing to the high mortality rates observed in these populations. Uremic toxins seem to be the potential “missing link.” Indoxyl sulfate (I...

Full description

Bibliographic Details
Main Authors: Fangfang Xiang, Xuesen Cao, Bo Shen, Xiaohong Chen, Man Guo, Xiaoqiang Ding, Jianzhou Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Medicine
Subjects:
T cell
indoxyl sulfate
aryl hydrocarbon receptor
chronic kidney disease
RNA-sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00178/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00178/full

Similar Items