Examining the Role of Cone-expressed RPE65 in Mouse Cone Function

Abstract Efficient chromophore supply is paramount for the continuous function of vertebrate cone photoreceptors. It is well established that isomerization of all-trans- to 11-cis- retinoid in the retinal pigmented epithelium by RPE65 is a key reaction in this process. Mutations in RPE65 result in a...

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Bibliographic Details
Main Authors: Alexander V. Kolesnikov, Peter H. Tang, Vladimir J. Kefalov
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-018-32667-w