RhoA- and Actin-Dependent Functions of Macrophages from the Rodent Cardiac Transplantation Model Perspective -Timing Is the Essence

The small GTPase RhoA, and its down-stream effector ROCK kinase, and the interacting Rac1and and mTORC2 pathways, are the principal regulators of the actin cytoskeleton and actin-related functions in all eukaryotic cells, including the immune cells. As such, they also regulate the phenotypes and fun...

Full description

Bibliographic Details
Main Authors: Malgorzata Kloc, Ahmed Uosef, Martha Villagran, Robert Zdanowski, Jacek Z. Kubiak, Jarek Wosik, Rafik M. Ghobrial
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/2/70