Loss of Serine-Type D-Ala-D-Ala Carboxypeptidase DacA Enhances Prodigiosin Production in Serratia marcescens

Loss of Serine-Type D-Ala-D-Ala Carboxypeptidase DacA Enhances Prodigiosin Production in Serratia marcescens

Serratia marcescens, a gram-negative bacterium, found in a wide range of ecological niches can produce several high-value products, including prodigiosin, althiomycin, and serratamolide. Among them, prodigiosin has attracted attention due to its immunosuppressive, antimicrobial, and anticancer prope...

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Bibliographic Details
Main Authors: Xuewei Pan, Changhao Sun, Mi Tang, Chao Liu, Jianing Zhang, Jiajia You, Tolbert Osire, Yang Sun, Youxi Zhao, Meijuan Xu, Taowei Yang, Zhiming Rao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
D-Ala-Ala carboxypeptidase DacA
prodigiosin synthesis
prodigiosin leakage
feedback inhibition
Serratia marcescens
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00367/full

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https://www.frontiersin.org/article/10.3389/fbioe.2019.00367/full

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