Cryosectioning the intestinal crypt-villus axis: An ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells

The intestinal epithelium is a particularly attractive biological adult model to study epigenetic mechanisms driving adult stem cell renewal and cell differentiation. Since epigenetic modifications are dynamic, we have developed an original ex vivo approach to study the expression and epigenetic pro...

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Bibliographic Details
Main Authors: Audrey Vincent, Catherine Kazmierczak, Belinda Duchêne, Nicolas Jonckheere, Emmanuelle Leteurtre, Isabelle Van Seuningen
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114001585