Missense allele of a single nucleotide polymorphism rs2294008 attenuated antitumor effects of prostate stem cell antigen in gallbladder cancer cells

Missense allele of a single nucleotide polymorphism rs2294008 attenuated antitumor effects of prostate stem cell antigen in gallbladder cancer cells

Background: Prostate stem cell antigen (PSCA), an organ-dependent tumor suppressor, is down regulated in gallbladder cancer (GBC). It is anticipated that the missense allele C of the single nucleotide polymorphism (SNP) rs2294008 (T/C) in the translation initiation codon of the gene affects the gene...

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Bibliographic Details
Main Authors: Hiroe Ono, Dai Chihara, Fumiko Chiwaki, Kazuyoshi Yanagihara, Hiroki Sasaki, Hiromi Sakamoto, Hideo Tanaka, Teruhiko Yoshida, Norihisa Saeki, Keitaro Matsuo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Carcinogenesis
Subjects:
Association study
cancer susceptibility
gallbladder cancer
missense single nucleotide polymorphism
tumor suppressor
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2013;volume=12;issue=1;spage=4;epage=4;aulast=Ono

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http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2013;volume=12;issue=1;spage=4;epage=4;aulast=Ono

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