Genetically-engineered pig-to-baboon liver xenotransplantation: histopathology of xenografts and native organs.
Orthotopic liver transplantation was carried out in baboons using wild-type (WT, n = 1) or genetically-engineered pigs (α1,3-galactosyltransferase gene-knockout, GTKO), n = 1; GTKO pigs transgenic for human CD46, n = 7) and a clinically-acceptable immunosuppressive regimen. Biopsies were obtained fr...
Main Authors: | Burcin Ekser, Edwin Klein, Jing He, Donna B Stolz, Gabriel J Echeverri, Cassandra Long, Chih Che Lin, Mohamed Ezzelarab, Hidetaka Hara, Massimiliano Veroux, David Ayares, David K C Cooper, Bruno Gridelli |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22247784/pdf/?tool=EBI |
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