Ribonucleotide reductase inhibitors: a new look at an old target for radiosensitization
Ribonucleotide reductase, the rate limiting enzyme in the synthesis and repair of DNA, has been studied as a target for inhibition in the treatment of cancer for many years. While some researchers have focused on ribonucleotide reductase inhibitors as chemotherapeutic agents, particularly in hematol...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-01-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2011.00056/full |