The Influence of Proton Pump Inhibitors on the Fecal Microbiome of Infants with Gastroesophageal Reflux—A Prospective Longitudinal Interventional Study

The Influence of Proton Pump Inhibitors on the Fecal Microbiome of Infants with Gastroesophageal Reflux—A Prospective Longitudinal Interventional Study

Proton pump inhibitors (PPIs) are the standard therapy for gastroesophageal reflux disease. In adults, PPI treatment is associated with Clostridium difficile infections (CDI). In contrast to adults the microbiome of infants develops from sterility at birth toward an adult-like profile in the first y...

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Bibliographic Details
Main Authors: Christoph Castellani, Georg Singer, Karl Kashofer, Andrea Huber-Zeyringer, Christina Flucher, Margarita Kaiser, Holger Till
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
proton pump inhibitors
microbiome
infants
GERD
Clostridium difficile
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00444/full

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http://journal.frontiersin.org/article/10.3389/fcimb.2017.00444/full

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