Acellular Lung Scaffolds Direct Differentiation of Endoderm to Functional Airway Epithelial Cells: Requirement of Matrix-Bound HS Proteoglycans

Acellular Lung Scaffolds Direct Differentiation of Endoderm to Functional Airway Epithelial Cells: Requirement of Matrix-Bound HS Proteoglycans

Efficient differentiation of pluripotent cells to proximal and distal lung epithelial cell populations remains a challenging task. The 3D extracellular matrix (ECM) scaffold is a key component that regulates the interaction of secreted factors with cells during development by often binding to and li...

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Bibliographic Details
Main Authors: Sharareh Shojaie, Leonardo Ermini, Cameron Ackerley, Jinxia Wang, Stephanie Chin, Behzad Yeganeh, Mélanie Bilodeau, Manpreet Sambi, Ian Rogers, Janet Rossant, Christine E. Bear, Martin Post
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115000259

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http://www.sciencedirect.com/science/article/pii/S2213671115000259

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