Expression of COX-1, COX-2, 5-LOX and $$\hbox {CysLT}_2$$ CysLT2 in nasal polyps and bronchial tissue of patients with aspirin exacerbated airway disease

Expression of COX-1, COX-2, 5-LOX and $$\hbox {CysLT}_2$$ CysLT2 in nasal polyps and bronchial tissue of patients with aspirin exacerbated airway disease

Abstract Background Aspirin exacerbated respiratory disease (AERD) is a disease of the upper and lower airways. It is characterized by severe asthma, chronic sinusitis with nasal polyps (CRSwNP) and intolerance towards nonsteroidal analgesics (NSAR). Arachidonic acid (AA) metabolites play an importa...

Full description

Bibliographic Details
Main Authors: Monique Vorsprach, Christoph Arens, Stephan Knipping, Dörte Jechorek, Sabine Stegemann-Koniszewski, Eva Lücke, Jens Schreiber
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Asthma
Nasal polyps
Aspirin exacerbated respiratory disease
Arachidonic acid
Cyclooxygenases
Lipoxygenases
Online Access:https://doi.org/10.1186/s13223-019-0395-5

Internet

https://doi.org/10.1186/s13223-019-0395-5

Similar Items