Neural Stem Cell-based Intraocular Administration of Pigment Epithelium-derived Factor Promotes Retinal Ganglion Cell Survival and Axon Regeneration after Optic Nerve Crush Injury in Rat: An Experimental Study

Background: Pigment epithelium-derived factor (PEDF) is regarded as a multifunctional protein possessing neurotrophic and neuroprotective properties. PEDF has a very short half-life, and it would require multiple injections to maintain a therapeutically relevant level without a delivery system. Howe...

Full description

Bibliographic Details
Main Authors: Wei-Min Zhang, Zhi-Ren Zhang, Yong-Gang Zhang, Yan-Sheng Gao
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2016-09-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:http://ijms.sums.ac.ir/index.php/IJMS/article/view/2541