Neural Stem Cell-based Intraocular Administration of Pigment Epithelium-derived Factor Promotes Retinal Ganglion Cell Survival and Axon Regeneration after Optic Nerve Crush Injury in Rat: An Experimental Study
Background: Pigment epithelium-derived factor (PEDF) is regarded as a multifunctional protein possessing neurotrophic and neuroprotective properties. PEDF has a very short half-life, and it would require multiple injections to maintain a therapeutically relevant level without a delivery system. Howe...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Shiraz University of Medical Sciences
2016-09-01
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Series: | Iranian Journal of Medical Sciences |
Subjects: | |
Online Access: | http://ijms.sums.ac.ir/index.php/IJMS/article/view/2541 |