Behavioral characterization of a mouse model overexpressing DSCR1/ RCAN1.

DSCR1/ RCAN1 is a chromosome 21 gene found to be overexpressed in the brains of Down syndrome (DS) and postulated as a good candidate to contribute to mental disability. However, even though Rcan1 knockout mice have pronounced spatial learning and memory deficits, the possible deleterious effects of...

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Bibliographic Details
Main Authors: Mara Dierssen, Gloria Arqué, Jerome McDonald, Nuria Andreu, Carmen Martínez-Cué, Jesús Flórez, Cristina Fillat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21364922/pdf/?tool=EBI