Cell type-specific effects of p27KIP1 loss on retinal development

Cell type-specific effects of p27KIP1 loss on retinal development

Abstract Background Cyclin-dependent kinase (CDK) inhibitors play an important role in regulating cell cycle progression, cell cycle exit and cell differentiation. p27KIP1 (p27), one of the major CDK inhibitors in the retina, has been shown to control the timing of cell cycle exit of retinal progeni...

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Bibliographic Details
Main Authors: Mariko Ogawa, Fuminori Saitoh, Norihiro Sudou, Fumi Sato, Hiroki Fujieda
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Neural Development
Subjects:
Cyclin-dependent kinase inhibitor
p27KIP1
Retinal development
Ectopic cell cycle reentry
Cone death
Online Access:http://link.springer.com/article/10.1186/s13064-017-0094-1

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http://link.springer.com/article/10.1186/s13064-017-0094-1

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