Marine Seagrass Extract of <i>Thalassia testudinum</i> Suppresses Colorectal Tumor Growth, Motility and Angiogenesis by Autophagic Stress and Immunogenic Cell Death Pathways

Marine plants have become an inexhaustible reservoir of new phytopharmaceuticals for cancer treatment. We demonstrate in vitro/in vivo antitumor efficacy of a standardized polyphenol extract from the marine angiosperm <i>Thalassia testudinum</i> (TTE) in colon tumor cell lines (RKO, SW48...

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Main Authors: Ivones Hernández-Balmaseda, Idania Rodeiro Guerra, Ken Declerck, José Alfredo Herrera Isidrón, Claudina Pérez-Novo, Guy Van Camp, Olivier De Wever, Kethia González, Mayrel Labrada, Adriana Carr, Geovanni Dantas-Cassali, Diego Carlos dos Reis, Livan Delgado-Roche, Roberto Rafael Nuñez, René Delgado-Hernández, Miguel David Fernández, Miriam T. Paz-Lopes, Wim Vanden Berghe
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/19/2/52