Neurotropin Inhibits Lipid Accumulation by Maintaining Mitochondrial Function in Hepatocytes via AMPK Activation

Neurotropin Inhibits Lipid Accumulation by Maintaining Mitochondrial Function in Hepatocytes via AMPK Activation

The accumulation of lipid droplets in the cytoplasm of hepatocytes, known as hepatic steatosis, is a hallmark of non-alcoholic fatty liver disease (NAFLD). Inhibiting hepatic steatosis is suggested to be a therapeutic strategy for NAFLD. The present study investigated the actions of Neurotropin (NTP...

Full description

Bibliographic Details
Main Authors: Qinglan Wang, Zhijun Wang, Mingyi Xu, Wei Tu, I-Fang Hsin, Aleksandr Stotland, Jeong Han Kim, Ping Liu, Mitsuru Naiki, Roberta A. Gottlieb, Ekihiro Seki
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
AMPK
fatty liver
mitochondria
lipid metabolism
liver
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00950/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00950/full

Similar Items