The dark side of dendritic cells: development and exploitation of tolerogenic activity that favour tumour outgrowth and immune escape
Dendritic cells (DC) play a central role in the regulation of the immune responses by providing the information needed to decide between tolerance, ignorance or active responses. For this reason different therapies aim at manipulating DC to obtain the desired response, such as enhanced cell-mediated...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-12-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00419/full |