The dark side of dendritic cells: development and exploitation of tolerogenic activity that favour tumour outgrowth and immune escape

Dendritic cells (DC) play a central role in the regulation of the immune responses by providing the information needed to decide between tolerance, ignorance or active responses. For this reason different therapies aim at manipulating DC to obtain the desired response, such as enhanced cell-mediated...

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Bibliographic Details
Main Authors: Barbara eSeliger, Chiara eMassa
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00419/full