Astrocyte atrophy and immune dysfunction in self-harming macaques.

Self-injurious behavior (SIB) is a complex condition that exhibits a spectrum of abnormal neuropsychological and locomotor behaviors. Mechanisms for neuropathogenesis could include irregular immune activation, host soluble factors, and astrocyte dysfunction.We examined the role of astrocytes as modu...

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Bibliographic Details
Main Authors: Kim M Lee, Kevin B Chiu, Hope A Sansing, Fiona M Inglis, Kate C Baker, Andrew G MacLean
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724606?pdf=render