CCL21/CCR7 Axis Contributed to CD133+ Pancreatic Cancer Stem-Like Cell Metastasis via EMT and Erk/NF-κB Pathway.

Tumor metastasis is driven by malignant cells and stromal cell components of the tumor microenvironment. Cancer stem cells (CSCs) are thought to be responsible for metastasis by altering the tumor microenvironment. Epithelial-mesenchymal transition (EMT) processes contribute to specific stages of th...

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Bibliographic Details
Main Authors: Lirong Zhang, Dongqing Wang, Yumei Li, Yanfang Liu, Xiaodong Xie, Yingying Wu, Yuepeng Zhou, Jing Ren, Jianxin Zhang, Haitao Zhu, Zhaoliang Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4978474?pdf=render