Exploring the Interaction of Curaxin CBL0137 with G-Quadruplex DNA Oligomers

Curaxins and especially the second-generation derivative curaxin CBL0137 have important antitumor activities in multiple cancers such as glioblastoma, melanoma and others. Although most of the authors suggest that their mechanism of action comes from the activation of p53 and inactivation of NF-kB b...

Full description

Bibliographic Details
Main Authors: Sabrina Dallavalle, Luce M. Mattio, Roberto Artali, Loana Musso, Anna Aviñó, Carme Fàbrega, Ramon Eritja, Raimundo Gargallo, Stefania Mazzini
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/12/6476