Sox-2 Positive Neural Progenitors in the Primate Striatum Undergo Dynamic Changes after Dopamine Denervation.

The existence of endogenous neural progenitors in the nigrostriatal system could represent a powerful tool for restorative therapies in Parkinson's disease. Sox-2 is a transcription factor expressed in pluripotent and adult stem cells, including neural progenitors. In the adult brain Sox-2 is e...

Full description

Bibliographic Details
Main Authors: Cristina Ordoñez, Paz Moreno-Murciano, Maria Hernandez, Carla Di Caudo, Iñaki-Carril Mundiñano, Iñaki Carril-Mundiñano, Nerea Vazquez, Jose Manuel Garcia-Verdugo, Rosario Sanchez-Pernaute, Maria-Rosario Luquin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688912?pdf=render