Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity.

A growing interest in asparagine (Asn) metabolism has currently been observed in cancer and infection fields. Asparagine synthetase (AS) is responsible for the conversion of aspartate into Asn in an ATP-dependent manner, using ammonia or glutamine as a nitrogen source. There are two structurally dis...

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Bibliographic Details
Main Authors: Joana Faria, Inês Loureiro, Nuno Santarém, Sandra Macedo-Ribeiro, Joana Tavares, Anabela Cordeiro-da-Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4714757?pdf=render