PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line

<p>Abstract</p> <p>Background</p> <p>Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia (ATL), whereas HTLV type 2 (HTLV-2), is not associated with ATL or any other leukemia. HTLV-1 encodes the transforming gene <it>tax1<...

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Bibliographic Details
Main Authors: Tanaka Yuetsu, Oie Masayasu, Takahashi Masahiko, Higuchi Masaya, Tsubata Chikako, Gejyo Fumitake, Fujii Masahiro
Format: Article
Language:English
Published: BMC 2005-07-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/46