Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling

Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling

Oxidative stress and energy imbalance strongly correlate in neurodegenerative diseases. Repeated concussion is becoming a serious public health issue with uncontrollable adverse effects in the human population, which involve cognitive dysfunction and even permanent disability. Here, we demonstrate t...

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Bibliographic Details
Main Authors: Shafiq Ur Rehman, Muhammad Ikram, Najeeb Ullah, Sayed Ibrar Alam, Hyun Young Park, Haroon Badshah, Kyonghwan Choe, Myeong Ok Kim
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
rmTBI
melatonin
AMPK
CREB
neurodegeneration
amyloid beta
synaptic dysfunction
Online Access:https://www.mdpi.com/2073-4409/8/7/760

Internet

https://www.mdpi.com/2073-4409/8/7/760

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