The Effects of Low Dose Naltrexone on Opioid Induced Hyperalgesia and Fibromyalgia

Objectives: While opioids temporarily alleviate pain, the overshoot of balancing pain drivers may increase pain, leading to opioid induced hyperalgesia (OIH). Our goal was to find out what chronic opioid treatment does to pain tolerance as measured by the cold pressor test (CPT), an objective measur...

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Bibliographic Details
Main Authors: Daniel Jackson, Sunita Singh, Yanli Zhang-James, Stephen Faraone, Brian Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.593842/full