Detection of K76T Mutation in pfcrt Gene as an Applicable Ge-netic Marker for Prediction of Chloroquine Resistant falciparum Malaria in Isolates from an Endemic District of Iran

Detection of K76T Mutation in pfcrt Gene as an Applicable Ge-netic Marker for Prediction of Chloroquine Resistant falciparum Malaria in Isolates from an Endemic District of Iran

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Background: This study investigated the association between pfcrt, T76 allele and chloroquine resistance in patients with falciparum malaria. Molecular assays for point mutations on drugs resistance-related genes are applied tools for monitoring emerging resistance and surveillance malaria control s...

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Bibliographic Details
Main Authors: A Raeisi, H Keshavarz, SR Naddaf, H Uemura, H Kanbara, MR Razavi, M Assmar, M Nateghpou, AR Esmaeili Rastaghi, M Mohebali
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2008-04-01
Series:Iranian Journal of Parasitology
Subjects:
Plasmodium falciparum
chloroquine resistance
pfcrt
K76T
Iran
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/9169.pdf&manuscript_id=9169

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http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/9169.pdf&manuscript_id=9169

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