The type III secretion effector NleE inhibits NF-kappaB activation.

The complex host-pathogen interplay involves the recognition of the pathogen by the host's innate immune system and countermeasures taken by the pathogen. Detection of invading bacteria by the host leads to rapid activation of the transcription factor NF-kappaB, followed by inflammation and era...

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Bibliographic Details
Main Authors: Chen Nadler, Kobi Baruch, Simi Kobi, Erez Mills, Gili Haviv, Marganit Farago, Irit Alkalay, Sina Bartfeld, Thomas F Meyer, Yinon Ben-Neriah, Ilan Rosenshine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2813277?pdf=render