Challenges in validating candidate therapeutic targets in cancer
More than 30 published articles have suggested that a protein kinase called MELK is an attractive therapeutic target in human cancer, but three recent reports describe compelling evidence that it is not. These reports highlight the caveats associated with some of the research tools that are commonly...
Main Authors: | Jeffrey Settleman, Charles L Sawyers, Tony Hunter |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/32402 |
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