Defective differentiation of adipose precursor cells from lipodystrophic mice lacking perilipin 1.

Defective differentiation of adipose precursor cells from lipodystrophic mice lacking perilipin 1.

Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and hydrolysis in adipocytes. Plin1 defect leads to low adiposity in mice and partial lipodystrophy in human. This study investigated the roles of Plin1 in adipocyte differentiation. Plin1 null (-/-) mice...

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Bibliographic Details
Main Authors: Ying Lyu, Xueying Su, Jingna Deng, Shangxin Liu, Liangqiang Zou, Xiaojing Zhao, Suning Wei, Bin Geng, Guoheng Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4335001?pdf=render

Internet

http://europepmc.org/articles/PMC4335001?pdf=render

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