Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons.

The Rac1 and Rac3 GTPases are co-expressed in the developing nervous system, where they are involved in different aspects of neuronal development, including the formation of synapses. The deletion of both Rac genes determines a stronger reduction of dendritic spines in vitro compared to the knockout...

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Bibliographic Details
Main Authors: Roberta Pennucci, Irene Gucciardi, Ivan de Curtis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220496