Identification of genetic loci affecting the severity of symptoms of Hirschsprung disease in rats carrying Ednrbsl mutations by quantitative trait locus analysis.

Identification of genetic loci affecting the severity of symptoms of Hirschsprung disease in rats carrying Ednrbsl mutations by quantitative trait locus analysis.

Hirschsprung's disease (HSCR) is a congenital disease in neonates characterized by the absence of the enteric ganglia in a variable length of the distal colon. This disease results from multiple genetic interactions that modulate the ability of enteric neural crest cells to populate developing...

Full description

Bibliographic Details
Main Authors: Jieping Huang, Ruihua Dang, Daisuke Torigoe, Chuzhao Lei, Xianyong Lan, Hong Chen, Nobuya Sasaki, Jinxi Wang, Takashi Agui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4366197?pdf=render

Internet

http://europepmc.org/articles/PMC4366197?pdf=render

Similar Items