Immunization with tegument nucleotidases associated with a subcurative praziquantel treatment reduces worm burden following Schistosoma mansoni challenge

Immunization with tegument nucleotidases associated with a subcurative praziquantel treatment reduces worm burden following Schistosoma mansoni challenge

Schistosomiasis is a debilitating disease caused by flatworm parasites of the Schistosoma genus and remains a high public health impact disease around the world, although effective treatment with Praziquantel (PZQ) has been available since the 1970s. Control of this disease would be greatly improved...

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Bibliographic Details
Main Authors: Henrique K. Rofatto, Bogar O. Araujo-Montoya, Patrícia A. Miyasato, Julio Levano-Garcia, Dunia Rodriguez, Eliana Nakano, Sergio Verjovski-Almeida, Leonardo P. Farias, Luciana C.C. Leite
Format: Article
Language:English
Published: PeerJ Inc. 2013-04-01
Series:PeerJ
Subjects:
Schistosoma mansoni
Vaccine
SmNTPDase Apyrase ATPDase
Alkaline phosphatase
Nucleotide pyrophosphatase/phosphodiesterase SmNPP NPP
Tegument
Online Access:https://peerj.com/articles/58.pdf

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https://peerj.com/articles/58.pdf

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