Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives

Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives

Abstract Background Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. A series of bis-pyrimidine Schiff bases were synthesized and screened for its antimicrobial and anticancer potential...

Full description

Bibliographic Details
Main Authors: Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Manikandan Selvaraj, Balasubramanian Narasimhan
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Chemistry Central Journal
Subjects:
Bis-pyrimidine Schiff bases
Antimicrobial
Anticancer
Molecular docking
Online Access:http://link.springer.com/article/10.1186/s13065-017-0322-0

Internet

http://link.springer.com/article/10.1186/s13065-017-0322-0

Similar Items