TMPRSS2-ERG expression predicts prostate cancer survival and associates with stromal biomarkers.

The TMPRSS2-ERG gene fusion is found in approximately half of all prostate cancers. The functional and prognostic significance of TMPRSS2-ERG is, however, not fully understood. Based on a historical watchful waiting cohort, an association between TMPRSS2-ERG, evaluated as positive immune staining, a...

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Bibliographic Details
Main Authors: Christina Hägglöf, Peter Hammarsten, Kerstin Strömvall, Lars Egevad, Andreas Josefsson, Pär Stattin, Torvald Granfors, Anders Bergh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914792?pdf=render