Rab7 associates with early endosomes to mediate sorting and transport of Semliki forest virus to late endosomes.

Semliki forest virus (SFV) is internalized by clathrin-mediated endocytosis, and transported via early endosomes to late endosomes and lysosomes. The intracellular pathway taken by individual fluorescently labeled SFV particles was followed using immunofluorescence in untransfected cells, and by vid...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-07-01
Series:PLoS Biology
Online Access:http://dx.doi.org/10.1371/journal.pbio.0030233