Insilico study of alkaloids as α-glucosidase inhibitors: Hope for the discovery of effective lead compounds

α-glucosidase (EC 3.2.1.20) is a primary carbohydrate metabolizing enzyme that acts on the 1-4 associated α-glucose residues. The inhibition of α-glucosidase slows down the process of carbohydrate digestion and avoids postprandial hyperglycemia, which is a major cause of chronic diabetes-associated...

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Bibliographic Details
Main Authors: Muhammad Zafar, Haroon Khan, Dr. Abdur Rauf, Ajmal Khan, Muhammad Arif Lodhi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00153/full