Toward Understanding the Mechanisms of Malignant Peripheral Nerve Sheath Tumor Development

Toward Understanding the Mechanisms of Malignant Peripheral Nerve Sheath Tumor Development

Malignant peripheral nerve sheath tumors (MPNSTs) originate from the neural crest lineage and are associated with the neurofibromatosis type I syndrome. MPNST is an unmet clinical need. In this review article, we summarize the knowledge and discuss research perspectives related to (1) the natural hi...

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Bibliographic Details
Main Authors: Teddy Mohamad, Camille Plante, Jean-Philippe Brosseau
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
neurofibromatosis type I
malignant peripheral nerve sheath tumor
neurofibroma
mouse models
tumor microenvironment
Online Access:https://www.mdpi.com/1422-0067/22/16/8620

Internet

https://www.mdpi.com/1422-0067/22/16/8620

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