Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis

Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis

Current therapies for multiple sclerosis (MS) are largely palliative, not curative. Mesenchymal stem cells (MSCs) harbor regenerative and immunosuppressive functions, indicating a potential therapy for MS, yet the variability and low potency of MSCs from adult sources hinder their therapeutic potent...

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Bibliographic Details
Main Authors: Xiaofang Wang, Erin A. Kimbrel, Kumiko Ijichi, Debayon Paul, Adam S. Lazorchak, Jianlin Chu, Nicholas A. Kouris, Gregory J. Yavanian, Shi-Jiang Lu, Joel S. Pachter, Stephen J. Crocker, Robert Lanza, Ren-He Xu
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114001271

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http://www.sciencedirect.com/science/article/pii/S2213671114001271

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