Immediate Neutrophil-Variable-T Cell Receptor Host Response in Bacterial Meningitis

Immediate Neutrophil-Variable-T Cell Receptor Host Response in Bacterial Meningitis

Bacterial meningitis is a life-threatening disease that evokes an intense neutrophil-dominated host response to microbes invading the subarachnoid space. Recent evidence indicates the existence of combinatorial V(D)J immune receptors in neutrophils that are based on the T cell receptor (TCR). Here,...

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Bibliographic Details
Main Authors: Tina Fuchs, Kerstin Puellmann, David H. Dreyfus, Armin P. Piehler, Björn Reuter, Christopher Schwarzbach, Olaf Willmann, Diego Yepes, Victor Costina, Peter Findeisen, Jens Mahrt, Chunlin Wang, Jian Han, Alexander W. Beham, Michael Neumaier, Wolfgang E. Kaminski
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neurology
Subjects:
bacterial meningitis
T cell receptors
neutrophil granulocytes
V(D)J receptors
phagocytosis
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00307/full

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https://www.frontiersin.org/article/10.3389/fneur.2019.00307/full

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