Relationships between IL-17A and Macrophages or MUC5AC in Eosinophilic Chronic Rhinosinusitis and Proposed Pathological Significance

Recently, some researchers have reported that macrophages and neutrophils were related to severe asthma. Mucus hypersecretion and persistent airway inflammation result from increased expression of mucin gene (MUC5AC). Eosinophilic chronic rhinosinusitis (ECRS) is considered as intractable rhinosinus...

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Bibliographic Details
Main Authors: Noritsugu Ono M.D., Takeshi Kusunoki M.D., Ph.D., Katsuhisa Ikeda M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2012-09-01
Series:Allergy & Rhinology
Online Access:https://doi.org/10.2500/ar.2012.3.0030