Stability study of oxaliplatin and doxorubicin for intraperitoneal administration with hyperthermia

Objective: To evaluate the in vitro physicochemical stability of oxaliplatin anddoxorubicin when the in vivo hyperthermic intraperitoneal conditions arereproduced. Methods: Three solutions were prepared, A (oxaliplatin 200 mg/L), B(doxorubicin 15 mg/L) and C (oxaliplatin 200 mg/L with doxorubicin 1...

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Bibliographic Details
Main Authors: V. Escudero-Ortiz, M.ª J. Duart-Duart, C. Pérez-Ruixo, J. J. Pérez-Ruixo, B. Valenzuela
Format: Article
Language:English
Published: Grupo Aula Médica 2014-05-01
Series:Farmacia Hospitalaria
Subjects:
Online Access:http://www.aulamedica.es/fh/pdf/1170.pdf