Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer.

BACKGROUND:The global gene expression profiles of adult and fetal murine prostate stem cells were determined to define common and unique regulators whose misexpression might play a role in the development of prostate cancer. METHODOLOGY/PRINCIPAL FINDINGS:A distinctive core of transcriptional regula...

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Main Authors: Roy Blum, Rashmi Gupta, Patricia E Burger, Christopher S Ontiveros, Sarah N Salm, Xiaozhong Xiong, Alexander Kamb, Holger Wesche, Lisa Marshall, Gene Cutler, Xiangyun Wang, Jiri Zavadil, David Moscatelli, E Lynette Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2684642?pdf=render