A persistent mitochondrial deletion reduces fitness and sperm performance in heteroplasmic populations of <it>C. elegans</it>

<p>Abstract</p> <p>Background</p> <p>Mitochondrial DNA (mtDNA) mutations are of increasing interest due to their involvement in aging, disease, fertility, and their role in the evolution of the mitochondrial genome. The presence of reactive oxygen species and the near l...

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Bibliographic Details
Main Authors: Chin Kara, Deshommes Cleonique, Gonzalez-Serricchio Aidyl S, Liau Wei-Siang, LaMunyon Craig W
Format: Article
Language:English
Published: BMC 2007-03-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/8/8