Identification of competing endogenous RNAs of the tumor suppressor gene PTEN: A probabilistic approach

Abstract Regulation by microRNAs (miRNAs) and modulation of miRNA activity are critical components of diverse cellular processes. Recent research has shown that miRNA-based regulation of the tumor suppressor gene PTEN can be modulated by the expression of other miRNA targets acting as competing endo...

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Bibliographic Details
Main Authors: Kourosh Zarringhalam, Yvonne Tay, Prajna Kulkarni, Assaf C. Bester, Pier Paolo Pandolfi, Rahul V. Kulkarni
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08209-1