Changes in B and T-cell subsets and NMO-IgG/AQP-4 levels after immunoglobulins and rituximab treatment for an acute attack of neuromyelitis optica

Background: There is increasing evidence supporting that neuromyelitis optica (NMO) is an inflammatory humoral mediated disorder associated with NMO-IgG/AQP-4 antibodies. However, little is known about the subsets of B cells and T cells that contribute to the pathogenesis or therapy response. Object...

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Bibliographic Details
Main Authors: C. de Andrés, R. Teijeiro, A. Saiz, P. Fernández, S. Sánchez-Ramón
Format: Article
Language:English
Published: Elsevier España 2015-06-01
Series:Neurología (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2173580815000589